"Serious adverse events after COVID-19
vaccination are rare but may occur.
For public awareness and
in the interest of transparency, CDC is providing timely updates on the
following serious adverse events of interest:
- Anaphylaxis after COVID-19
vaccination is rare and
has occurred in approximately 2 to 5 people per million vaccinated in the
United States. Severe allergic reactions, including
anaphylaxis, can occur after any vaccination. If this occurs, vaccination
providers can effectively and immediately treat the reaction. Learn more
about COVID-19 vaccines and allergic reactions, including anaphylaxis.
- Thrombosis with
thrombocytopenia syndrome (TTS) after Johnson & Johnson’s Janssen
(J&J/Janssen) COVID-19 vaccination is rare. As of June 21, 2021, more than 12 million doses of the
J&J/Janssen COVID-19 Vaccine have been given in the United States. CDC
and FDA identified 36 confirmed reports of people who got the
J&J/Janssen COVID-19 Vaccine and later developed TTS. Women younger
than 50 years old especially should be aware of the rare but increased
risk of this adverse event. There are other COVID-19 vaccine options
available for which this risk has not been seen. Learn more about J&J/Janssen COVID-19 Vaccine
and TTS.
- To date, one confirmed case of
TTS following mRNA COVID-19 vaccination (Moderna) has been reported to
VAERS after more than 306 million doses of mRNA COVID-19 vaccines administered in
the United States. Based on available data, there is not an increased
risk for TTS after mRNA COVID-19 vaccination.
- Myocarditis and pericarditis
after COVID-19 vaccination are rare. As of June 21, 2021, VAERS has received 616 reports of myocarditis or
pericarditis among people
ages 30 and younger who received COVID-19 vaccine. Most cases
have been reported after mRNA COVID-19 vaccination (Pfizer-BioNTech or
Moderna), particularly in male adolescents and young adults. Through follow-up,
including medical record reviews, CDC and FDA have confirmed 393 reports of
myocarditis or pericarditis. CDC and its partners are investigating
these reports to assess whether there is a relationship to COVID-19
vaccination. Learn more about COVID-19 vaccines and myocarditis.
- Reports of death after COVID-19
vaccination are rare. More
than 318 million doses of COVID-19 vaccines were administered in the
United States from December 14, 2020, through June 21, 2021. During this
time, VAERS received 5,479 reports of death (0.0017%) among people who
received a COVID-19 vaccine. FDA requires healthcare providers to report
any death after COVID-19 vaccination to VAERS, even if it’s unclear
whether the vaccine was the cause. Reports of adverse events to
VAERS following vaccination, including deaths, do not necessarily mean that
a vaccine caused a health problem. A review of available clinical
information, including death certificates, autopsy, and medical records,
has not established a causal link to COVID-19 vaccines. However, recent reports
indicate a plausible causal relationship between the J&J/Janssen COVID-19 Vaccine and TTS,
a rare and serious adverse event—blood clots with low platelets—which has
caused deaths."
Source: https://www.cdc.gov/coronavirus/2019-ncov/vaccines/safety/adverse-events.html